Acute renal failure – definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group

Acute renal failure – definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group
 

Key messages

The first consensus definition of acute renal failure (ARF) has now been developed. It is called RIFLE, the initials reflecting the terms Risk, Injury, Failure, Loss and End

Stage in relation to kidney function. It is presented in this article.

The body responsible for the consensus definition of ARF is the Acute Dialysis Quality Initiative (ADQI) group, which conducted a consensus conference for this purpose.

The ADQI group reviewed animal models of ARF and classified them according to their features, usefulness, relevance and reproducibility. They are summarized in Table 4.

The ADQI group reviewed the issue of end-points for trials or studies in ARF and summarized the advantages and disadvantages of different end-point in different investigational situations.

The ADQI group reviewed issues of technology as they relate to the treatment of acute renal failure and developed general principles for future developments in renal support technology.

All issues are discussed in details on the webpage of ADQI http://www.ADQI.net

Critical Care 2004, 8:R204-R212 (Full Text PDF)